Overview

The ability of cells to perceive and correctly respond to their environment is the basis of development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in the interplay, dynamics or localization of the involved molecules are responsible for many diseases such as cancer, autoimmunity and diabetes. By increasing the understanding of the complex interplay between these various components and their dynamics over time the related diseases can be treated more effectively.

Because of the recent technological revolution in advanced light microscopy (i.e. functional imaging of molecules, development of caged compounds and biosensors) it is now possible to directly monitor the dynamics of these (single) molecules and numerous biosensors in living cells.  Microscopic techniques like Super-resolution Microscopy, FLIM-FRET, FRAP and FCS allow us to visualize cellular signaling complexes and their dynamics in time and will be the topic of this FEBS practical course.

This 6-day advanced microscopy course for up to 20 experienced graduate students, postdocs and scientists will integrate theoretical lectures with hands-on experiments and practical experience. National and international experts in the field of microscopy will give an overview of “state-of-the-art” imaging techniques and applications in biological research.

Organisers and supporters